Job description
Lead and perform instrument systems engineering, analysis, modeling and integration on Thermo Fisher’s Genetic Analysis Platforms: CE Sanger Sequencing and qPCR.
Responsibilities/Primary focus:
Responsibilities/Primary focus:
- Development of instruments and systems for upstream sequencing workflows including, but not limited to, sample extraction, library preparation, CE sequencing or qPCR.
- Work with a group of product development scientists and engineers focused on the development of new sequencing and sample preparation platforms.
- The successful candidate will be the nexus of all new platform integration and design starting at the prototype stage and continuing through manufacturing.
- This role also requires working closely with manufacturing partners, external vendors and our business community, to produce robust processes that deliver high quality instrument platform products Thermo Fisher.
- BA or greater in Engineering, Chemistry or Physics.
- Minimum 10 years experience with one or more of the following:
- Developing automated instrument systems that integrate disposable microliter scale reaction vessels with flow-in/flow-out reagents.
- Developing liquid handling systems
- Experience developing optical detection systems for sequencing or genetic analysis
- Experience in integrating new and complex technologies
- Track record of successful launch of a complex consumable and instrument.
- Strong self starter and fast learner
- Skills in Solidworks and FEA modeling (CMSOL or equivalent)
- Skills in Matlab, Mathematica, IgorPro and other data analysis and modeling tools.
- Skills in instrument software control e.g. Labview, Python
- Familiar with common molecular biology laboratory methods such as PCR, cloning, and enzymology
- Have strong knowledge of Systems Design for Six Sigma (DFSS)
- Experience developing under ISO13485 a plus.
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